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Latanoprost acid

Latanoprost acid
Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about lowering pressure inside the eyes.
Catalog No. T15718Cas No. 41639-83-2
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Purity:96.97%
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Latanoprost acid

Catalog No. T15718Cas No. 41639-83-2

Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about lowering pressure inside the eyes.
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Pack SizePriceAvailabilityQuantity
1 mg$52In Stock
5 mg$148In Stock
10 mg$238In Stock
25 mg$477In Stock
50 mg$708In Stock
100 mg$972In Stock
200 mg$1,290In Stock
1 mL x 10 mM (in DMSO)$163In Stock
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Product Introduction

Bioactivity
Description
Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about lowering pressure inside the eyes.
In vitro
Latanoprost acid (10, 20 μM) reduces the protein expressions of c-fos and NFATc1 thus inhibiting the mature osteoclast formation in BMMs. Latanoprost acid (10μM) and RANKL(50ng/ml) significantly inhibit ERK, p38, AKT and JNK[1].
In vivo
Latanoprost acid (i.p.; 20 mg/kg; once daily for 7 days) effectively prevents LPS-induced bone destruction [1].
Chemical Properties
Molecular Weight390.51
FormulaC23H34O5
Cas No.41639-83-2
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 27.5 mg/mL (70.42 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5608 mL12.8038 mL25.6075 mL128.0377 mL
5 mM0.5122 mL2.5608 mL5.1215 mL25.6075 mL
10 mM0.2561 mL1.2804 mL2.5608 mL12.8038 mL
20 mM0.1280 mL0.6402 mL1.2804 mL6.4019 mL
50 mM0.0512 mL0.2561 mL0.5122 mL2.5608 mL

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